School of Medicine

The Pulse - June 2023

Seen in the Papers

Congratulations to the following individuals for publication of their work in respective journals from February 1 through April 30, 2023 as reported to The Pulse. 

This list is compiled from submissions by faculty and staff – it is only as complete as the information we receive. Please let us know about your publication by emailing Denise at dflock@lsuhsc.edu.

Anatomy and Radiology

A student-led, collaborative project between the departments of anatomy and radiology led to the publication of A Problem of Gender Representation: Adapting the Bechdel Test to Evaluate the Social Media Presence of Radiology Residency Programs in Current Problems in Diagnostic Radiology 

Olivia Purcell, Caroline Galliano, Molly Lieux, William Gibson, Emma Schachner, Bradley Spieler, Sonya Van Nuland.

Internal Medicine:

Dr. Cynthia Brown recently published two manuscripts focused on hospital associated disability. Up to 30% of older adults leave the hospital with a decline in the ability to complete their activities of daily living when compared to before admission. This proportion has been unchanged for three decades, despite significant changes in how healthcare is provided:

Dr. Christine Butts (Emergency Medicine), Dr. Ben DeBoisblanc, Dr. Stephen Kantrow and Dr. Matt Lammi (Pulmonary/ Critical Care) recently published in American Thoracic Society (ATS) Scholar on a longitudinal ultrasound curriculum.

Dr. Paul Harch (Emergency Medicine) was invited to guest edit a special research topic in Frontiers in Neurology, titled Review of Hyperbaric Therapy & Hyperbaric Oxygen Therapy in the Treatment of Neurological Disorders. The focus of these articles will be a review of the literature on hyperbaric therapy/hyperbaric oxygen therapy for acute to chronic neurological disorders according to the dose of oxygen, pressure, and "inert” breathing gases employed.

Dr. Paul LeLorier (Cardiology) recently published with LSU neurology colleagues on Change in sudomotor function (autonomic nervous system control of sweat gland activity) after COVID-19 infection. These findings were reported in eNeurologicalSci, a Journal of the World Federation of Neurology. (Aditi Varma-Doyle, Nicole R Villemarette-Pittman, Paul Lelorier, John England)

Dr. Mihran Naljayan (Nephrology) recently published a paper on the Impact of the COVID-19 pandemic and lessons learned regarding home dialysis. The authors found the clinical benefits seen in home over center-based dialysis treatment were more apparent during the COVID-19 pandemic, but increased utilization of home dialysis did not occur. (Naljayan, Mihran V.; Schiller, Brigitte; Watnick, Suzanne; Weinhandl, Eric D.; Perl, Jeffrey)

Microbiology, Immunology and Parasitology

Yalcin D, Bennet SJ, Sheehan J, Trauth AJ, Tso FY, West JT, Hagensee ME, Ramsay AJ, Wood C. Longitudinal variations in antibody responses against SARS-CoV-2 spike epitopes upon serial vaccinations. International Journal of Molecular Sciences 2023 24, 7292. doi.org/10.3390/ijms24087292

Milligan EC, Olstad K, Williams CA, Mallory M, Cano P, Cross KA, Munt JE, Garrido C, Lindesmith L, Watanabe J, Usachenko JL, Hopkins L, Immareddy R, Shaan Lakshmanappa Y, Elizaldi SR, Roh JW, Sammak RL, Pollard RE, Yee JL, Herbek S, Scobey T, Miehlke D, Fouda G, Ferrari G, Gao H, Shen X, Kozlowski PA, Montefiori D, Hudgens MG, Edwards DK, Carfi A, Corbett KS, Graham BS, Fox CB, Tomai M, Iyer SS, Baric R, Reader R, Dittmer DP, Van Rompay KKA, Permar SR, De Paris K. Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later. Science Transl Med 2023 Mar;15(685):eadd6383. doi: 10.1126/scitranslmed

Jennings S, Hu Y, Wellems D, Luo M, Scull C, Taylor CM, Nauseef WM, Wang G. Neutrophil Defect and Lung Pathogen Selection in Cystic Fibrosis. J Leukoc Biol. 2023 Mar 20; doi:10.1093/jleuko/qiad033. [Epub ahead of print]. PMID: 36976023.

Muzny CA, Van Gerwen OT, Schroeder JA, Kay-Duncan ES, Siwakoti K, Aaron KJ, Eastlund IC, Graves KJ, Elnaggar JH, Tamhane A, Long D, Van Wagoner N, Toh E, Taylor CM. Impact of Testosterone Use on the Vaginal Microbiota of Transgender Men, including Susceptibility to Bacterial Vaginosis: Study Protocol for a Prospective, Observational Study. BMJ Open. 2023 Mar 27;13(3):e073068. doi: 10.1136/bmjopen-2023-073068. PMID: 36972958. PMCID: PMC10069580.

Babalola CM, Peters RPH, Mukomana F, Mdingi M, Gigi RMS, Muzny CA, Taylor CM, Medina Marino A, Klausner JD. A Call to Standardize the Definition and Method of Assessing Women for Vaginal Discharge Syndrome in Pregnancy. Open Forum Infect Dis. 2023 Apr;10(4):ofad157. doi: 10.1093/ofid./ofad157. eCollection 2023 Apr. PMID: 37035494. PMCID: PMC10077826.

Elnaggar JH, Lammons JW, Taylor CM, Toh E, Ardizzone CM, Dong A, Aaron KJ, Luo M, Tamhane A, Lefkowitz EJ, Quayle AJ, Nelson DE, Muzny CA. Characterization of Vaginal Microbial Community Dynamics in the Pathogenesis of Incident Bacterial Vaginosis, a Pilot Study. Sex Transm Dis. 2023 Apr 17. doi: 10.1097/ OLQ.0000000000001821. Online ahead of print PMID: 37074327. PMCID: NIHMS1892337.

Muzny CA, Sobel J., Elnaggar JH, Taylor CM, Van Der Pol B. State of the art for diagnosis of bacterial vaginosis. Journal of Clinical Microbiology, in press.

Xu JY, Liu XY, Zhang W, Feng WZ, Liu MX, Yang LY, Yang ZX, Zhang HF, Zhang ZG, Wang P. Hydrophobic cue-induced appressorium formation depends on MoSep1-mediated MoRgs7 phosphorylation and internalization in Magnaporthe oryzae. PLoS Genetics, in press.

Ophthalmology

Chawla H, Uhr JH, Williams JS, Reinoso MA, Weiss JS. Economic Evaluation of Artificial Intelligence Systems versus Manual Screening for Diabetic Retinopathy in the United States. Ophthalmic Surgery, Lasers, and Imaging Retina. 2023 May; 0(0): 1-9 [e-publication ahead of print]. (Dr. Chawla, PGY3, Dr. Williams, PGY4, Dr. Reinoso, Assoc Prof & Residency Program Director, Dr. Weiss, Dept Chair)

Chawla H, Goldblatt JS, Morgan JE, Barron BA, Rao AK, Reinoso MA. Central Retinal Artery Occlusion with Concomitant Intracranial Hemorrhage Secondary to Streptococcus Gordonii Endocarditis. Case Reports in Ophthalmological Medicine. 2023 May; [in press]. (Dr. Chawla, PGY3, Dr. Goldblatt, PGY2, Dr. Morgan, PGY4, Dr. Barron, Professor, Dr. Rao, Assoc Prof & Fellowship Program Director, Dr. Reinoso, Assoc Prof & Residency Program Director)

Chawla H, Pahng JN, Benevento JD, Mazzulla DA, Puri S, Eustis HS. Subretinal Abscess Complicated by Post-Infectious Retinal Vasculitis Following Strabismus Surgery. Journal of Pediatric Ophthalmology & Strabismus. 2023 Feb; [in press]. (Dr. Chawla, PGY3, Dr. Pahng, Residency Alumnus)

Thompson JP, Hattier, GA, Bozner, EM, Wood, JJ, Kirchner, KR. Progressive Cranial Polyneuropathy from Neurotropic Melanoma. Journal of Neuro-Ophthalmology. 2023 May; [published online ahead of press]. (Dr. Thompson, PGY3, Ms. Bozner, SOM L4, Dr. Kirchner, Associate Professor, Medical Student Director)

Otolaryngology – Head and Neck Surgery

Kuhn, M.A., Gillespie, M.B., Ishman, S.L., Ishii, L.E., Brody, R., Cohen, E., Dhar, S.I., Hutcheson, K., Jefferson, G., Johnson, F., Rameau, A., Sher, D., Starmer, H., Strohl, M., Ulmer, K., Vaitaitis, V., Begum, S., Batjargal, M. and Dhepyasuwan, N. (2023), Expert Consensus Statement: Management of Dysphagia in Head and Neck Cancer Patients. Otolaryngology–Head and Neck Surgery, 168: 571-92. https://doi.org/10.1002/ohn.302

Peer reviewed journal article:

Wilde DC, Kansara S, Banner L, Morlen R, Hernandez DJ, Huang AT, Mai W, Fuller CD, Lai S, Sandulache VC. Early detection of mandible osteoradionecrosis risk in a high comorbidity veteran population. Am J Otolaryngol 2022; 44(2): 103781.

Book chapter:

Kansara S, Kraus D, Ha P. Oral Cavity, Pharynx, and Larynx Anatomy, Physiology, and Other Basics. Essential Head and Neck Oncology and Surgery. 13th edition. Accepted for publication. Nova Science Publishers.  

Pediatrics

Dr. Marcella Houser cowrote an article entitled "Weight Stigma and Bias: A Guide for Pediatric Clinicians" which was recently published in the Obesity Pillars. (Amy Braddock, Nancy T. Browne, Marcella Houser, Giselle Blair, Dominique R. Williams)

Dr. Alexis Morvant's research "Patterns of Pediatric Palliative and End-of-Life Care in Neonatal Intensive Care Patients in the Southern U.S. was published in the Journal of Pain and Symptom Management (JPSM) this quarter. (Erin R. Currie, PhD, RN; Joanne Wolfe, MD, MPH; Renee Boss, MD, MHS; Emily E. Johnston, MD, MS; Christian Paine, MD; Samuel J. Perna, DO; Susan Buckingham, MD; Kathleen M. McKillip, MD; Peng Li, PhD; James N. Dionne-Odom, PhD, RN; Deborah Ejem, PhD; Alexis Morvant, MD, MA; Catherine Nichols, APRN, CPNP-AC/PC; Marie A. Bakitas, DNSc, NP-C)

Dr. Morvant was also published recently for an American Academy of Pediatrics (AAP) Ethics Module: Conflict of Interest in Pediatrics. Click here to read the chapter. 

Drs. Alexis Morvant and Ashley Kiefer partnered on the research article "The Landscape of Outpatient Pediatric Palliative Care: A National Cross-Sectional Assessment" which was published in the Journal of Pain and Symptom Management (JPSM). (Ashley K. Autrey, MD; Casie James, MD; Suraj Sarvode Mothi, MPH; Caroline Stafford, BS; Alexis Morvant, MD, MA; Elissa G. Miller, MD; Erica C. Kaye, MD, MPH)

Dr. Amanda Dumas's research was published in the Southern Medical Journal (SMJ). The article is entitled "A Survey of Louisiana Pediatricians’ Approach to Parenting Teens and Adolescent Reproductive Health." (S. Amanda Dumas, MD, MSc, Nikka Khorsandi, MD, MPH)

Dr. Ryan Pasternak recently published an article entitled "21st Century Cures Act ONC Rule: Implications for Adolescent Care and Confidentiality Protections" in the American Academy of Pediatrics. (Ryan H. Pasternak, MD, MPH, FAAP; Elizabeth M. Alderman, MD, FAAP; Abigail English, JD)

Dr. Kayla Phelps recently published an article entitled "Children with Severe Sepsis: Relationship Between Community Level Income and Morbidity and Mortality." (Kayla B. Phelps, Acham Gebremariam, Erica Andrist, Ryan P. Barbaro, Gary L. Freed, and Erin F. Carlton)

Dr. Phelps also recently published an article in Critical Care Medicine titled “Health Disparities in Extracorporeal Membrane Oxygenation Utilization and Outcomes: A Scoping Review and Methodologic Critique of the Literature.” (Katie M. Moynihan, MBBS, FRACP, FCICM; Anna Dorste, MLIS; Faraz Alizadeh, MD; Kayla Phelps, MD, MPH; Jessica A. Barreto, MD, MS; Amy R. Kolwaite, ARNP, MS, MPH; Anthony Merlocco, MD, MSt, FSCMR; Ryan P. Barbaro, MD, MSc; Titus Chan, MD, MS, MPP; Ravi R. Thiagarajan, MBBS, 
MPH)

Physiology

Secci ME, Reed T, Quinlan V, Gilpin NW, Avegno EM (2023). Quantitative analysis of gene expression in RNAscope-processed brain tissue. Bio-protocol. 13(0): e4580. Selected for cover art in January 2023 issue.

Barattini AE, Montanari C, Edwards KN, Edwards S, Gilpin NW, Pahng AR (2023). Chronic inflammatory pain promotes fentanyl place preference in male rats but does not change fentanyl self-administration in male and female rats. Neuropharmacology 231:109512.

Bourgeois BL, Levitt DE, Molina PE, Simon L (2023). Differential expression of adipocyte and myotube extracellular vesicle miRNA cargo in chronic binge alcohol-administered SIV-infected male macaques. Alcohol. 10.1016/j.alcohol.2022.11.001. PMID: 36351490

Cucinello-Ragland JA, Edwards S (2023). The hidden risks of alcohol use for pain relief. Alcohol: Clinical and Experimental Research 47(2): 209-210.

Dubic MG, Edwards S, McDaniel LS, Simon L, Molina PE (2023). Differential regulation of tachykinin and opioid system gene expression in brain and immune cells of chronic binge alcohol-treated, simian immunodeficiency virus (SIV)-infected macaques. AIDS Research and Human Retroviruses. PMID: 36351490.

Edwards S, Ferguson TF, Gasparini S, Mercante DE, Molina PE, Gunaldo TP (2023). Interprofessional education as a potential foundation for future team-based prevention of alcohol use disorder. BMC: Medical Education 23:126.

Fitzpatrick-Schmidt TF, Edwards S (2023). Cortisol as a risk biomarker of recovery from substance use disorders. Alcohol: Clinical and Experimental Research 47(3):435-437.

Lopez M, Davis EC, Cucinello-Ragland JA, Regunathan S, Edwards S, Becker HC (2023). Agmatine reduces alcohol drinking and alleviates hyperalgesia symptoms in rodent models of alcohol use disorder. Alcohol 109:23-33.

Varodayan FP, Pahng AR, Davis TD, Bajo M, Steinman MQ, Kiosses WB, Blednov YA, Burkart MD, Edwards S, Roberts AJ, Roberto M (2023). Alcohol dependence induces a pro-inflammatory switch in interleukin-1-beta signaling of GABAergic signaling in the mouse medial prefrontal cortex. Brain, Behavior, and Immunity 110:125-139.

Savedchuk S, Phachu D, Shankar M, Sparks MA, Harrison-Bernard LM (2023). Targeting Glomerular Hemodynamics for Kidney Protection. Advances in Kidney Disease and Health. 30(2):71-84. doi: 10.1053/j.akdh.2022.12.003. PMID: 36868736.

Zhao P, Mondal S, Martin C, DuPlissis A, Chizari S, Ma KY, Maiya R, Messing RO, Jiang N, Ben-Yakar A (2023). Femtosecond laser microdissection for isolation of regenerating C. elegans neurons for single-cell RNA sequencing. Nat Methods. doi: 10.1038/s41592-023-01804-3. PMID: 36928074.

Psychiatry

Shatto, E.H., Stefurak, J., Rinner, A.E., & Kantra, L.M. (2023). Trauma-informed supervision: The supervisory needs of mental health therapists engaged in trauma-related work. Journal of Counselor Preparation and Supervision, 17(2). 

Osofsky JD, Fields-Olivieri MA, Frazer AL, Graham RA, McCurdy BH and Weems CF (2023) What to Look for in Relationships: Development, inter-rater reliability, and initial validity estimates for a young child-caregiver relationship assessment. Frontiers in Psychology 14:1157665. doi: 10.3389/fpsyg.2023.1157665

Osofsky, J.D. and Osofsky, H.J. (In press, 2023). Preparation and Response to Disasters, COVID-19 Pandemic, Terrorism and War: The Importance of Building Coalitions. APA Handbook of Pediatric Psychology, Developmental-Behavioral Pediatrics, and Developmental Science. Washington, DC: American Psychological Association.

Books:

Mulrooney, K., Osofsky, J.D., Keren, M. (2023, in press). DC:0-5 Casebook. Washington, DC.: Zero to Three Press