School of Medicine

The Pulse - June 2024

Seen in the Papers

Congratulations to the following individuals for publication of their work in respective journals from February 1 – April 30, 2024 as reported to The Pulse.

This list is compiled from submissions by faculty and staff – it is only as complete as the information we receive. Please let us know about your publication by emailing Denise at dflock@lsuhsc.edu.

Cardiovascular Center of Excellence

Elgazzaz M, Filipeanu C, Lazartigues E. The 2023 Lewis K. Dahl Memorial Lecture: Angiotensin-Converting Enzyme 2 Posttranslational Modifications-Implications for Hypertension and SARS-CoV-2 Infection. Hypertension. 2024 Apr 3. doi: 10.1161/HYPERTENSIONAHA.124.22067. Epub ahead of print. PMID: 38567498.

Elgazzaz M, Berdasco C, Garai J, Baddoo M, Lu S, Daoud H, Zabaleta J, Mauvais-Jarvis F, Lazartigues E. Maternal Western diet programs cardiometabolic dysfunction and hypothalamic inflammation via epigenetic mechanisms predominantly in the male offspring. Mol Metab. 2024 Feb;80:101864. doi: 10.1016/j.molmet.2023.101864. Epub 2023 Dec 28. PMID: 38159883; PMCID: PMC10806294.

Ahmed O, Ekumi KM, Nardi FV, Maisumu G, Moussawi K, Lazartigues ED, Liang B, Yakoub AM. Stable, neuron-specific gene expression in the mouse brain. J Biol Eng. 2024 Jan 16;18(1):8. doi: 10.1186/s13036-023-00400-5. PMID: 38229168; PMCID: PMC10790494.

 

Genetics

How can Academic Health Science Centers Help to Increase Diversity in the STEM Professions?” in Frontiers in Education-Language, Culture and Diversity.                             Mary Moore, Martha Cuccia, Alicia Edwards, Chindo Hicks, Angela Mclean, Christian Nieves-Rivera, Gabrielle Sheets, Kelly Jean Sherman, Allison Augustus-Wallace and Fern Tsien* Article ID: 1357946

Bioinformatics Characterization of Variants of Uncertain Significance in Pediatric Sensorineural Hearing Loss” in Frontiers in Pediatrics-Pediatric Otolaryngology            Sloane Clay, Adele Evans, Regina Zambrano, David Otohinoyi, Chindo Hicks and Fern Tsien* Article ID: 1299341

Sulindac sulfide as a non-immune suppressive gamma-secretase modulator to target Triple-Negative Breast Cancer” in Frontiers in Immunology-Cancer Immunity and Immunotherapy                                                                                                                                  Fokhrul Hossain, Deniz A Ucar, Giulia Monticone, Yong Ran, Samarpan Majumder, Kristina Larter, Hanh Luu, Dorota Wyczechowska, Soroor Heidari, Keli Xu, Sudarvili Shanthalingam, Margarite Matossian, Yaguang Xi, Matthew Burow, Bridgette M Collins-Burow, Luis Del Valle, Chindo Hicks, Jovanny Zabaleta, Todd E Golde, Barbara A Osborne and Lucio Miele* Article ID : 1244159

Brock, Courtney & Kavalakatt, Joachim & Benz, Megan & Hawes, Mackenzie & Arbogast, Carter & Cullen, Nicole & McConnell, Emily & Rinderle, Caroline & Hebert, Katherine & Khosla, Maninder & Belgodere, Jorge & Hoang, Van & Collins-Burow, Bridgette & Bunnell, Bruce & Burow, Matthew & Alahari, Suresh. (2024). Obesity-associated epigenetic alterations and the obesity-breast cancer axis. Oncogene. 43. 10.1038/s41388-024-02954-0.

 

Internal Medicine

Dr. Allison Augustus-Wallace recently published two articles. The first paper was an editorial published in the BMJ (British Medical Journal) titled “Sense of belonging is a critical component of workforce retention.” “Equitable hiring strategies for a diversified faculty” was published online by ASBMB Today (the American Society for Biochemistry and Molecular Biology) and is a review of a recently published paper in Nature Biomedical Engineering.

Dr. Annalisa Perez (Nephrology) and Dr. Efrain Reisin (Nephrology) recently published Hyperuricemia: An Intriguing Connection to Metabolic Syndrome, Diabetes, Kidney Disease, and Hypertension in Current Hypertension Reports this review paper on the epidemiology, physiology, and clinical data surrounding the connection between hyperuricemia and metabolic syndrome, chronic kidney disease, and hypertension.

Dr. Mihran Naljayan (Nephrology) recently published a piece in the DaVita Newsroom titled “Who Will Inspire the Next Generation of Nephrologists?

Emergency Medicine colleagues including Dr. Kasha Bornstein (IM/ EM Resident), Dr. Elizabeth LaRosa (EM Resident), Dr. Kelsey Byrd (EM Resident) and Dr. Heather Murphy-Lavoie (Emergency Medicine) recently published When Educational Images Don't Reflect the Population: Phlegmasia Cerulea Dolens, a Case Report in Clinical Practice and Cases in Emergency Medicine. The team described a case of Phlegmasia Cerulea Dolens in a patient with a darker skin complexion and highlighted distinctions in exam findings in patients of color.

Dr. Omar Leonards (Cardiology Fellow) recently published the online editorial titled PAD: A Clue to Polyvascular Disease in Need of Federal Legislative Reconsideration in the American College of Cardiology.

Dr. Paul Harch (Emergency Medicine) recently published Review of Hyperbaric Therapy and Hyperbaric Oxygen Therapy in the Treatment of Neurological Disorders According to Dose of Pressure and Hyperoxia in the Frontiers in Neurology and is also the Guest Editor of a Research Topic in Frontiers in Neurology, Experimental Therapeutics and Neurotrauma.

Dr. Ben Springgate and team’s work with the Community Resilience Learning Collaborative and Research Network (Section of Community and Population Medicine, including Dr. Ashley Wennerstrom and Dr. Richard Culbertson) resulted in a book chapter entitled "Community Partnered Participatory Research in Southeast Louisiana Communities Threatened by Climate Change: The C-LEARN EXPERIENCE" being published this month in Challenging Cases in Clinical Research Ethics (Taylor and Francis, Oxford, England). 

 

Microbiology, Immunology and Parasitology

Muzny CA, Elnaggar JH, Sousa LGV, Lima A, Aaron KJ, Eastlund IC, Graves KJ, Dong C, Van Gerwen OT, Luo M, Tamhane A, Long D, Cerca N, Taylor CM. Microbial interactions among Gardnerella, Prevotella, and Fannyhessea prior to incident bacterial vaginosis: protocol for a prospective, observational study. BMJ Open. 2024 Feb 5;14(2):e083516. doi: 10.1136/bmjopen-2023-083516. PMID: 38316599. PMCID: PMC10859992.

Nessim Kostandy E, Suh JH, Tian X, Okeugo B, Rubin E, Shirai S, Luo M, Taylor CM, Kim KH, Marc Rhoads J, Liu Y. Probiotic Limosilactobacillus reuteri DSM 17938 Changes Foxp3 Deficiency-Induced Dyslipidemia and Chronic Hepatitis in Mice. Nutrients. 2024 Feb 12;16(4), 511. doi: 10.3390/nu16040511. PMID: 38398835. PMCID: PMC10892585.

Byerley LO, Lorenzen B, Chang HM, Hartman WG, Keenan MJ, Page R, Luo M, Dowd SE, Taylor CM. Gut Microbial Dysbiosis Differs in Two Distinct Cachectic Tumor-Bearing Models Consuming the Same Diet. Nutrients. 2024 Apr 6;16(7):1076. doi: 10.3390/nu16071076. PMID: 38613109. PMCID: PMC11013133.

Zaparte A, Dore E, White S, Paliarin F, Gabriel C, Copenhaver K, Basavanhalli S, Garcia E, Vaddavalli R, Luo M, Taylor CM, Welsh D, Maiya R. Standard Rodent Diets Differentially Impact Alcohol Consumption and Preference and Gut Microbiome Diversity. Frontiers Neuroscience. [Accepted Apr 12 2024].

Verma A, Hawes CE, Elizaldi SR, Smith JC, Rajasundaram D, Pedersen GK, Shen X, Williams LD, Tomaras GD, Kozlowski PA, Amara RR, Iyer SS. Tailoring Tfh profiles enhances antibody persistence to a clade C HIV-1 vaccine in rhesus macaques. Elife. 2024 Feb 22;12:RP89395. doi: 10.7554/eLife.89395.PMID: 38385642

 

Ophthalmology

Chawla H, Uhr JH, Williams JS, Reinoso MA, Weiss JS. Economic Evaluation of Artificial Intelligence Systems Versus Manual Screening for Diabetic Retinopathy in the United States. Ophthalmic Surg Lasers Imaging Retina. 2023 May;54(5):272-280. doi: 10.3928/23258160-20230406-01. Epub 2023 May 1. PMID: 37078827.2.

Weiss JS, Rapuano CJ, Seitz B, BGusin M, Kivela T, Bouheraoua N, Bredrup C, Nischal KK, Chawla H, Borderie V, Kenyon KR, Kim EK, Moller HU, Munier FL, Berger T, Lisch W. IC3D Classification of Corneal Dystrophies-Edition 3. Cornea. 2024, Feb 12. DOI: 10.1097/ICO.0000000000003420

Weiss JS, Afshari NA. Corneal Guttae Alone Do Not Make A Diagnosis of Fuchs Endothelial Corneal Dystrophy. Am J Ophthalmol. 2024 Feb 23:S0002-9394(24)00070-9. doi: 10.1016/j.ajo.2024.02.014.

 

Orthopaedic Surgery

Drs. Robert Zura and Jessica Rivera participated in the research study Skin Antisepsis before Surgical Fixation of Extremity Fractures published February 1 in the New England Journal of Medicine.

 

Pathology

Dr. Yu Liu’s Blastoma of the Digestive System in Adults: A Review was accepted for publication in the World Journal of Gastrointestinal Surgery.

Acute neutrophilic vasculitis (leukocytoclasia) in 36 COVID-19 autopsy brains,” Roy H. Rhodes, Gordon L. Love, Fernanda Da Silva Lameira, Maryam Sadough Shahmirzadi, Sharon E. Fox, Richard S. Vander Heide. Diagn Pathol 19, 33 (2024). https://doi.org/10.1186/s13000-024-01445-w

Dr. Asra Feroze and Dr. Ritu Bhalla’s “Condyloma Acuminata” was published in Pathology Outlines.

 

Otolaryngology

Kansara S, Oral E, Sarkar I, Mualla R, Walvekar R, et al. Rate of occult metastasis in lip squamous cell carcinoma: A systematic review and meta-analysis. Head & Neck. 2024;1‐7. doi:10.1002/hed.27747

Issa CP, Nunez A, Mualla R, Kansara S. Imaging of extranodal lymphomas in the head and neck: A case series and review of the literature. Case Rep Clin Radiol. doi: 10.25259/CRCR_13_2024

Sheehan, D., Mantle, B., Kraft, A., Craver, R., Arcement, C., Gardner, R., … Nuss, D. (2024). Primary Intraosseous Granular Cell Tumor of the Sphenoid and Central Skull Base in a Pediatric Patient. Fetal and Pediatric Pathology, 1–6. https://doi.org/10.1080/15513815.2024.2315455

Poche JN, Hernandez SC, Melder KL, Dunham ME, Nuss DW, Fang Z. Endoscopic surgical field clarity index: An artificial intelligence-based measure of transnasal endoscopic surgical field quality. Int Forum Allergy Rhinol. 2024 Apr 22. doi: 10.1002/alr.23348. Epub ahead of print. PMID: 38648256.

 

Pediatrics

Dr. Regina Zambrano, Associate Professor in the Pediatric Genetics Division, recently published the open access article Bioinformatics Characterization of Variants of Uncertain Significance in Pediatric Sensorineural Hearing Loss in Frontiers in Pediatrics, section Pediatric Otolaryngology.

Dr. Amanda Dumas recently co-authored a paper published in Public Health Reports entitled "The Utility of Virtual Home Visits to Reduce Asthma Burden in Low-Income Black Communities in Louisiana During the COVID-19 Pandemic."

Allergy/Immunology faculty Drs. Luke Wall and Elizabeth Wisner recently co-authored a paper published in Frontiers in Allergy entitled "Development of IgE-mediated Food Allergies in Children with History of Food Protein-induced Allergic Proctocolitis: A Series of Five Cases."

Dr. Kayla Phelps (Critical Care Division) co-authored "Understanding Disparities in the ICU: A Scoping Review" in Pediatrics.

 

Physiology

Danielle E Levitt, Brianna L Bourgeois, Keishla M Rodríguez-Graciani, Patricia E Molina, Liz Simon. Alcohol Impairs Bioenergetics and Differentiation Capacity of Myoblasts from Simian Immunodeficiency Virus-Infected Female Macaques. Int J Mol Sci. 2024. doi: 10.3390/ijms25042448

 

Psychiatry

Section of Psychology:

The WAIMH Handbook of Infant and Early Childhood Mental Health, which was published in 2024 and co-edited by Dr. Joy Osofsky, features a chapter by Dr. Amy Dickson and colleagues titled “Diversity-Informed Practice for Parent/Caregiver Relationship Assessment.”