Publications

 

Adjunctive therapy with an oral H₂S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction. 

Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE 3rd, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E, Shah SJ, Li Z, Lefer DJ.Br J Pharmacol. 2024 Jul 9. doi: 10.1111/bph.16493. Online ahead of print.PMID: 38982742

Upregulation of inflammatory genes and pathways links obesity to severe COVID-19. 

Currey J, Ellsworth C, Khatun MS, Wang C, Chen Z, Liu S, Midkiff C, Xiao M, Ren M, Liu F, Elgazzaz M, Fox S, Maness NJ, Rappaport J, Lazartigues E, Blair R, Kolls JK, Mauvais-Jarvis F, Qin X.Biochim Biophys Acta Mol Basis Dis. 2024 Jun 26;1870(7):167322. doi: 10.1016/j.bbadis.2024.167322. Online ahead of print.PMID: 38942338 Free article.

Angiotensin-Converting Enzyme 2 Posttranslational Modifications and Implications for Hypertension and SARS-CoV-2: 2023 Lewis K. Dahl Memorial Lecture. 

Elgazzaz M, Filipeanu CM, Lazartigues E.Hypertension. 2024 Jul;81(7):1438-1449. doi: 10.1161/HYPERTENSIONAHA.124.22067. Epub 2024 Apr 3.PMID: 38567498 Review.

Stable, neuron-specific gene expression in the mouse brain. 

Ahmed O, Ekumi KM, Nardi FV, Maisumu G, Moussawi K, Lazartigues ED, Liang B, Yakoub AM.J Biol Eng. 2024 Jan 16;18(1):8. doi: 10.1186/s13036-023-00400-5.PMID: 38229168 Free PMC article.

Maternal Western diet programs cardiometabolic dysfunction and hypothalamic inflammation via epigenetic mechanisms predominantly in the male offspring. 🗍

Elgazzaz M, Berdasco C, Garai J, Baddoo M, Lu S, Daoud H, Zabaleta J, Mauvais-Jarvis F, Lazartigues E.Mol Metab. 2024 Feb;80:101864. doi: 10.1016/j.molmet.2023.101864. Epub 2023 Dec 28.PMID: 38159883 Free PMC article.

 Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high-fat diet. 

Whitehead AK, Li Z, LaPenna KB, Abbes N, Sharp TE, Lefer DJ, Lazartigues E, Yue X.Am J Physiol Heart Circ Physiol. 2024 Jan 1;326(1):H278-H290. doi: 10.1152/ajpheart.00474.2023. Epub 2023 Dec 1.PMID: 38038717