Below are clinical trials open pertaining to gynecologic cancers with LSU Health New Orleans.
Cervical Cancer
Evaluating the addition of the immunotherapy drug atezolizumab to standard chemotherapy treatment for advanced or metastatic neuroendocrine carcinomas that originate outside the lung.
A Phase II, Multicenter Study to Evaluate Efficay and Safety Using Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Recurrent, Metastatic or Persistent Cervical Carcinoma.
A Randomized Controlled Trial of Robotic vs. Open Radical Hysterectomy for Cervical Cancer (ROCC Trial)
Phase II trial of niraparib in combination with dostarlimab in patients with recurrent or progressive cervix cancer (STAR)
Ovarian Cancer
Randomized Phase III Trial of Paclitaxel/Carboplatin Followed by Maintenance Letrozole versus Letrozole monotherapy in Stage II-IV Low Grade Serous Carcinoma
Randomized, multicenter, open-label, phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-positive recurrent platinum-sensitive epithelial ovarian, fallopian tube
A phase Ib/2 basket study of CR-368 as monotherapy and in combination with gemcitabine in adult subjects with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma and urothelial carcinoma based on ACRIVON Oncosignature Status.
Uterine Cancer
Selinexor in Maintenance Therapy After Systemic Therapy for Participants with p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma (XPORT-EC-042) Rare Tumors.
Testing Olaparib and Temozolomide versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy has Stopped Working.
A randomized controlled trial looking at different modalities of social support for black women with endometrial cancer.
Endometrial Cancer Molecularly Targeted Therapy Consortium
A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined with Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma
A Phase III Trial Of The Impact Of Sentinel Lymph Node Mapping On Patient Reported Lower Extremity Limb Dysfunction In Endometrial Cancer
A phase Ib trial of vaginal cuff brachytherapy + pembrolizumab (MK3475) followed by 3 cycles of dose dense paclitaxel/q21 day carboplatin + pembrolizumab (MK3475) in high intermediate risk endometrial cancer
A phase Ib/2 basket study of CR-368 as monotherapy and in combination with gemcitabine in adult subjects with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma and urothelial carcinoma based on ACRIVON Oncosignature Status.
Cancer Control
DCP-001
Use of a Clinical Trial Screening Tool to Address Cancer Health Disparities in teh NCI Community Oncology Research Program (NCORP)
Cancer Symptom Management
DiRECT: An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors
A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]
Multicenter Randomized Controlled Trial Comparing Brief Behavioral Therapy for Cancer related Insomnia and Healthy Eating Education Learning