School of Medicine

Department of Pharmacology and Experimental Therapeutics

Selected publications

 (Click on PubMed ID to view abstract)

*To find additional publications by this author, please visit Pubmed Central, a National Institutes of Health-operated site for electronic distribution of life sciences research reports.

 

 

 

Key Publications

Shearn, CT, Pulliam CF, Pedersen K, Meredith K, Mercer KE, Saba LM, Orlicky, DJ, Ronis MJ and Petersen DR. GSTA4-/- Mice show Enhanced Protein Carbonylation, Inflammation, and Injury following EtOH Consumption. Alc. Clin. Exp. Res. 42: 1192-1205, 2018.

Watt, J., Alund, A.W., Pulliam, C.F., Mercer, K.E., Suva, L.S., Chen, J-R. and Ronis M.J.J. NOX4 deletion in mice exacerbates the effect of ethanol on trabecular bone loss and osteoblast colony formation, J. Pharmacol. Exp. Ther. 366: 46-57, 2018.

Ronis MJJ, Gomez-Acevedo H, Shankar K, Sharma N, Blackburn M, Singhal R, Mercer K and Badger T.M. Soy protein isolate does not act as a weak estrogen receptor agonist in the prepubertal rat testis. Exp. Biol. Med. 243: 695-707, 2018.

Mercer, KE, Pulliam CF, Pedersen KB, Hennings L, Lai K, Cleves MA, Jones EE, Drake RR and Ronis MJJ. Soy protein isolate inhibits high fat-induced hepatic tumor promotion in DEN-treated mice. Experimental Biology and Medicine. 242: 635-644, 2017.

Alund, A.W., Mercer, K.E., Pulliam, C.F., Suva, L.J., Chen, J-R., Badger, T.M. and Ronis M.J.J. Protection by dietary antioxidants against ethanol-induced osteopenia and changes in bone morphology in female mice. Alc. Clin. Exp. Res. 41: 46-56, 2017.

Zhang J., Lazarenko O.P., Kang J., Blackburn M.L., Ronis M.J.J., Badger T.M. and Chen J-R. Feeding blueberry diets to young rats dose-dependently inhibits bone resorption through suppression of RANKL in stromal cells. PLos One 8: e70438, 2013.

Chen, J-R., Zhang, J., Lazarenko, O.P., Cao, J., Blackburn, M.L., Badger, T.M. and Ronis, M.J.J. Soy Protein Isolates Prevent Loss of Bone Quantity Associated with Obesity in Rats through Regulation of Insulin Signaling in Osteoblasts, FASEB J. 27: 3514-3523, 2013.

Miousse I.R., Sharma N., Badeaux J., Hennings L., Shankar K., Gomez-Acevedo H., Cleves M.A., Badger T.M. and Ronis M.J.J. Mammary morphology and gene expression signature of prepubertal male and female rats following exposure to exogenous estradiol. Exp. Biol. Med. 238: 1033-1046, 2013.

Borengasser, S.J., Zhong, Y., Kang, P., Ronis, M.J.J., Badger, T.M., Gomez-Acevedo, H. and Shankar, K. Influence of Maternal Obesity on White Adipose Tissue Differentiation and DNA Methylation in the Offspring.  Endocrinology 154: 4113-4125, 2013.

Miousse I.R., Sharma, N., Vantrease, J., Hennings, L., Shankar, K., Gomez-Acevedo, H., Cleves, M.A., Badger,T.M. and Ronis, M.J.J. Feeding soy protein isolate and estradiol treatment have different effects on the morphology and gene expression signature of the mammary gland in prepubertal male and female rats. Physiological Genomics 45: 1072-1083, 2013.  

Ronis MJJ, Mercer K, Suva L,Vantrease J, Ferguson M, Hogue W, Sharma N, Blackburn M and Badger TM. Influence of fat/carbohydrate ratio on progression of fatty liver disease and on bone loss in male rats fed alcohol via total enteral nutrition (TEN). Alcohol 48:133-144, 2014.

Mercer KE, Sims C, Yang C, Wynne RA, Moutos C, Hogue WR, Lumpkin CK, Suva, LJ, Chen, J-R, Badger TM and Ronis MJJ. Loss of functional NADPH oxidase 2 protects against alcohol-induced bone resorption in female p47phox-/- mice chronically fed ethanol. Alc. Clin. Exp. Res. 38: 672-682, 2014.

Chen, J-R., Lazarenko, O.P., Zhang, J., Blackburn, M.L., Ronis,M.J.J. and Badger, T.M. Dietary Blueberry Polyphenol-Derived Phenolic Acids Direct Osteoblast and Adipocyte Lineage Commitment and Differentiation, J. Bone Min. Res. 29: 1043-1053, 2014.

Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough, Stiles BL, Ronis MJJ and Petersen DR. A high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice. PLos One 9:e96553, 2014.

Zhang, J., Lazarenko, O.P., Blackburn, M.L., Badger T.M., Ronis M.J.J. and Chen J-R. Soy protein isolates down-regulate caveolin-1 expression to suppress the osteoblastic cell senescence pathway, FASEB J.  28: 3134-3145, 2014.

Mercer KE, Hennings L, Sharma N, Lai K, Chandler C, Wynne RA, Cleves MA, Badger TM, and Ronis MJJ. Alcohol consumption promotes diethylnitrosamine-induced hepatocarcinogenesis in male mice through the activation of the Wnt/b catenin signaling pathway. Cancer Prevention Res. 7: 675-685, 2014.

Yang CS, Alund AW, Mercer KE, Suva LJ, Badger TM and Ronis MJJ. Genistein supplementation increases overall bone turnover but does not prevent alcohol-induced bone loss in male mice. Exp. Biol. Med. 239: 1380-1389, 2014.

Caro A, Bell M, Ejiofor S, Zurcher G, Petersen, D and Ronis MJJ. N-acetylcysteine inhibits the upregulation of mitochondrial biogenesis genes in livers from rats fed chronic ethanol. Alc. Clin. Exp.Res. 38: 2896-2906, 2014.

Mercer, K.E., Hennings, L., Badger, T.M. and Ronis M.J.J. Alcohol consumption,  oWnt/b-catenin signaling and hepatocarcinogensis. Adv. Exp. Biol. Med. 815: 185-195, 2015.

Ronis MJJ, Miousse IR, Mason AZ, Sharma N, Blackburn ML and Badger TM. Trace element status and zinc homeostasis differ in breast and formula-fed piglets. Exp. Biol. Med. 240: 58-66, 2015.

Ronis MJ, Chen Y, Badeaux J, Badger TM. Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling. J Nutr. 139: 1431-1438, 2009.

Singhal R, Shankar K, Badger TM, Ronis MJ. Hepatic gene expression following consumption of soy protein isolate in female Sprague-Dawley rats differs from that produced by 17{beta}-estradiol treatment. J Endocrinol. 202:141-52, 2009.

Chen J-R, Lazarenko OP, Blackburn ML, Badger TM and Ronis MJ. A role for ethanol-induced oxidative stress in controlling lineage commitment of mesenchymal stromal cells through inhibition of Wnt/beta catenin signaling. J. Bone Min. Res. 25: 1117-1127, 2010.

Chen J-R, Lazarenko OP, Wu X, Kang J, Blackburn ML, Shankar K, Badger TM and Ronis MJJ. Metabolites derived from blueberry polyphenols stimulate bone formation via p38 MAP kinase/Wnt-b-catenin signaling. J. Bone Min. Res. 25: 2399-2411, 2010.

Chen J-R, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Shankar K, Badger TM and Ronis MJJ. Obesity reduces bone mass through activation of PPARg and suppression of Wnt/b-catenin. PLos One 5: e13704, 2010.

Chen JR, Lazarenko OP, Shankar K, Blackburn ML, Lumpkin CK, Badger TM, Ronis MJ. Inhibition of NADPH oxidases prevents chronic ethanol-induced bone loss in female rats. J Pharmacol Exp Ther. 336:734-42, 2011.

Ronis MJJ, Hennings L, Stewart B, Basnakian AG, Apostolov EO, Albano E, Badger TM, and Petersen DR. Effects of long term ethanol administration in a rat total enteral nutrition model of alcoholic liver disease, Am. J. Physiol. Gastroent. Liver Physiol. 300: 110-119, 2011.

Ronis MJJ, Chen Y, Shankar K, Gomez-Acevedo H, Badeaux J, Blackburn ML and Badger TM. Formula feeding and protein source alter hepatic gene expression, iron and cholesterol homeostasis in neonatal piglets. Physiol. Genomics. 43: 1281-1293, 2011.

Mercer K, Wynne RA, Lazarenko OP, Lumpkin CK, Hogue WR, Suva L, Chen J-R, Mason AZ, Badger TM and Ronis MJJ. Vitamin D supplementation protects against bone loss associated with chronic alcohol administration in the female rat. J. Pharmacol. Exp. Ther. 343:401-412, 2012. 

Ronis MJJ, Baumgardner JN, Marecki J, Badeaux J, Sharma N, Blackburn ML, Till R, Tong Y, Kang J, Wu X, Cleves MA, Gomez-Acevedo H and Badger TM The Degree of Fatty Acid Saturation in a Diet Determines the Type of Steatosis and the Level of Pathology of the Liver in Obese Rats, Physiol. Genomics 44: 1073-1089, 2012.

Ronis MJJ, Shankar K, Gomez-Acevedo H, Hennings H, Singhal R, Blackburn ML and Badger TM. Mammary Gland Morphology and Gene Expression Differ in Female Rats Treated with 17b-Estradiol or Fed Soy Protein Isolate, Endocrinology 153: 6021-6032, 2012.

Ronis MJJ, Baumgardner JN, Sharma N, Badeaux J, Ferguson M, Tong Y, Wu X, Cleves MA and Badger TM. Medium chain triglycerides dose-dependently prevent liver pathology in a rat model of nonalcoholic liver disease. Exp. Biol. Med. 238: 151-162, 2013.

Ronis MJJ, Sharma N, Vantrease J, Borengasser SJ, Ferguson M, Gomez-Acevedo H. and Badger TM, Mice lacking NADPH-Oxidase Component p47phox are Protected Against High Fat Diet-Induced Obesity, Physiological Genomics 45: 351-366 2013.

*To find additional publications by this author, please visit Pubmed Central, a National Institutes of Health-operated site for electronic distribution of life sciences research reports.

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