School of Medicine

The Louisiana Lung Cancer Study

Scientific Articles:

  • J. E. Bailey-Wilson, C. I. Amos, S. Pinney, G. M. Petersen, M. de Andrade, J. S. Wiest, P. Fain, A. G. Schwartz, M. You, W. Franklin, C. Klein, A. Gazdar, H. Rothschild, D. M. Mandal, T. Coons, J. Slusser, J. Lee, C. Gaba, E. Kupert, A. Perez, X. Zhou, D. Zeng, Q. Liu, D. Seminara, J. Minna, M. Anderson. A major lung cancer susceptibility locus maps to chromosome 6q23-25. American Journal of Human Genetics. 2004. 75:460-484. PMID: 15272417.
  • M. Wang, H. Vikis, Y. Wang, D. Jia, D. Wang, L. J. Bierut, J. E. Bailey-Wilson, C. I. Amos, S. M. Pinney, G. P. Peterson, M. de Andrade, P. Yang, J. S. Wiest, P. R. Fain, A. G. Schwartz, A. Gazdar, J. Minna, C. Gaba, H. Rothschild, D. M. Mandal, E. Kupert, D. Seminara, Y. Liu, J. Clark, M. Watson, A. Viswanathan, R. Govindan, M. W. Anderson, M. You. Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. Cancer Research. 2007. 67:93-99. PMID: 17210687.
  • H. Vikis, M. Sato, M. James, D. Wang, Y. Wang, M. Wang, D. Jia, Y. Liu, J. E. Bailey-Wilson, C. I. Amos, S. M. Pinney, G. P. Peterson, M. de Andrade, P. Yang, J. S. Wiest, P. R. Fain, A. G. Schwartz, A. Gazdar, C. Gaba, H. Rothschild, D. M. Mandal, E. Kupert, D. Seminara, A. Viswanathan, R. Govindan, J. Minna, M. W. Anderson, M. You. EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Research. 2007. 67:4665-70. PMID: 17510392.
  • P. Liu, H.G. Vikis, D. Wang, Y. Lu, Y. Wang, A.G. Schwartz, S.M. Pinney, P. Yang, M. de Andrade, G.M. Petersen, J.S. Wiest, P.R. Fain, A. Gazdar, C. Gaba, H. Rothschild,  D.M. Mandal, T. Coons, J. Lee, E. Kupert, D. Seminara, J. Minna, J.E. Bailey-Wilson, M.R. Spitz, T. Eisen, R.S. Houlston, C.I. Amos, M.W. Anderson, M. You. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst. 2008. 100:1326-30. PMID: 18780872.
  • M. You, D. Wang, P. Liu, H. Vikis, M. James, Y. Lu, Y. Wang, M. Wang, D. Jia, Y.  Liu, L.J. Bierut, P. Yang, Z. Sun, Y.  Wu, W. Zheng, X. Shu, J. Long, Y. Gao, Y. Xiang, W. Chow, N. Rothman, S.M. Pinney, G.M. Petersen, M. de Andrade, J.S. Wiest, P.R. Fain, A.G. Schwartz, A. Gazdar, C. Gaba, H. Rothschild, D. M. Mandal, J. Lee, E. Kupert, D. Seminara, J. Minna, J.E. Bailey-Wilson, C. I. Amos, and M.W. Anderson. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 is a likely candidate gene. Clinical Cancer Research. 2009. 15:2666-74. PMID: 19351763.
  • Y. Liu, P. Liu, W. Wen, M. A. James, Y. Wang, J. E. Bailey-Wilson, C. I. Amos, S. M. Pinney, P. Yang, M. de Andrade, G. M. Petersen, J. S. Wiest, P. R. Fain, A. G. Schwartz, A. Gazdar, C. Gaba, H. Rothschild, D. M. Mandal, E. Kupert, J. Lee, D. Seminara, J. Minna, M. W. Anderson, and M. You. Haplotype and Cell Proliferation Analyses of Candidate Lung Cancer Susceptibility Genes on Chromosome 15q24-25.1. Cancer Research. 2009. 69:7844-50.PMID: 19789337.
  • J.C. Wang, C. Cruchaga, N.L. Saccone, S. Bertelsen, P. Liu, J.P. Budde, W. Duan, L. Fox, R.A. Grucza, J. Kern, K. Mayo, O. Reyes, J. Rice, S.F. Saccone, N. Spiegel, J.H. Steinbach, J.A. Stitzel, M.W. Anderson, M. You, V.L. Stevens, L.J. Bierut, A.M. Goate; COGEND collaborators and GELCC collaborators. Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet. 2009.18:3125-35. PMID: 19443489.
  • P. Liu, H.G. Vikis, D. Wang, Y. Lu, A.G. Schwartz, S.M. Pinney, P. Yang, M. de Andrade, A. Gazdar, C. Gaba, D.M. Mandal, J. Lee, E. Kupert, D. Seminara, J. Minna, J.E. Bailey-Wilson, C.I. Amos, M.W. Anderson, M. You. Cumulative Effect of Multiple Loci on Genetic Susceptibility to Familial Lung Cancer. Cancer Epidemiology, Biomarkers, & Prevention. 2010. 19:517-24. PMID: 20142248.
  • P. Liu, P. Yang, X. Wu, H. G. Vikis, Y. Lu, Y. Wang, A. G. Schwartz, S. M. Pinney, M. de Andrade, A. Gazdar, C.Gaba, D. M. Mandal, E. Kupert, D. Seminara, J. Minna, J. E. Bailey-Wilson, M. Spitz, C. I. Amos, M. W. Anderson, and M. You. A Second Genetic Variant on Chromosome 15q24-25.1 Associates with Lung Cancer. Cancer Research. 2010. 70:3128-35. PMID: 20395203.
  • C.I. Amos, S.M. Pinney, Y. Li, E. Kupert, J. Lee, M.A. de Andrade, P. Yang, A.G. Schwartz, P.R. Fain, A. Gazdar, J. Minna, J.S. Wiest, D. Zeng, H. Rothschild, D. M. Mandal, M. You, T. Coons, C. Gaba, J.E. Bailey-Wilson, M.W. Anderson. A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers. Cancer Research. 2010. 70:2359-67. PMID: 20215501.
  • D. Xiong, J-H. Lee, E. Kupert, C. Simpson, S.M. Pinney, C.R. Gaba, D. M. Mandal, Y. Wang, A.G. Schwartz, P. Yang, M. de Andrade, F. Ding, P. Cui, H. Jiang, D.D. Stambolian, M.R. Spitz, C.I. Amos, J.E. Bailey-Wilson, M. Anderson, J.H. Jeong,  M. You. A recurrent mutation in PARK2 in familial lung cancer. AJHG 2015. 96:301-308. PMID: 25640678.
  • Y. Liu, F. Kheradmand, C.F. Davis, M.E. Scheurer, D. Wheeler, S. Tsavachidis, G. Armstrong, C. Simpson, D.M. Mandal, E. Kupert, M. Anderson, M. You, D. Xiong, C. Pikielny, A.G. Schwartz, J.E. Bailey-Wilson, C. Gaba, M. De Andrade, P. Yang, S.M. Pinney; Genetic Epidemiology of Lung Cancer Consortium, C.I. Amos, M.R. Spitz. Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. J Thorac Oncol. 2016 Jan;11(1):52-61. doi: 10.1016/j.jtho.2015.09.015. PMID: 26762739.
  • A.M. Musolf, C.L. Simpson, M. de Andrade, D.M. Mandal, C. Gaba, P. Yang, Y. Li, M. You, E.Y. Kupert, M.W. Anderson, A.G. Schwartz, S.M. Pinney, C.I. Amos, J.E. Bailey-Wilson. Familial Lung Cancer: A Brief History from the Earliest Work to the Most Recent Studies. Genes (Basel). 2017 Jan 17;8(1). pii: E36. doi: 10.3390/genes8010036. Review. PMID: 28106732.
  • A.M. Musolf, C.L. Simpson, M. de Andrade, D.M. Mandal, C. Gaba, P. Yang, Y. Li, M. You, E.Y. Kupert, M.W. Anderson, A.G. Schwartz, S.M. Pinney, C.I. Amos, J.E. Bailey-Wilson. Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer. Hum Hered. 2017 Aug 18;82(1-2):64-74. doi: 10.1159/000479028. [Epub ahead of print] PubMed PMID: 28817824.
  • Y. Liu, C.M. Lusk, M.H. Cho, E.K. Silverman, D. Qiao, R. Zhang, M.E. Scheurer, F. Kheradmand, D.A. Wheeler, S. Tsavachidis, G. Armstrong, D. Zhu, I.I. Wistuba, C. B. Chow, C. Behrens, C.W. Pikielny, C. Neslund-Dudas, S.M. Pinney, M. Anderson, E. Kupert, J.E. Bailey-Wilson, C. Gaba, D.M. Mandal, M. You, M. de Andrade, P. Yang, J.K. Field, T. Liloglou, M. Davies, J. Lissowska, B. Swiatkowska, D. Zaridze, A. Mukeriya, V. Janout, I. Holcatova, D. Mates,  S. Milosavljevic, G. Scelo, P. Brennan, J. McKay, G. Liu, R.J. Hung, D.C. Christiani, A.G. Schwartz, C.I. Amos, M.R. Spitz. Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. J Thorac Oncol. 2018 Oct;13(10):1483-1495. doi: 10.1016/j.jtho.2018.06.016. Epub 2018 Jul 4. PMID: 29981437.
  • J. Byun, A.G. Schwartz, C. Lusk, A.S. Wenzlaff, M. de Andrade, D.M. Mandal, C. Gaba, P. Yang, M. You, E.Y. Kupert, M.W. Anderson, Y. Han, Y. Li, D. Qian, A. Stilp, C. Laurie, S. Nelson, W. Zheng, R.J. Hung, V. Gaborieau, J. Mckay, P. Brennan, N.E. Caporaso, M.T. Landi, X. Wu, J.R. McLaughlin, Y. Brhane, Y. Bossé, S.M. Pinney, J.E. Bailey-Wilson, C.I. Amos. Genome-wide association study of familial lung cancer. Carcinogenesis. 2018 Sep 21;39(9):1135-1140. doi: 10.1093/carcin/bgy080. PMID: 29924316.
  • A.M. Musolf, B.A. Moiz, H. Sun, C.W. Pikielny, Y. Bossé, D.M. Mandal, M. de Andrade, C. Gaba, P. Yang, Y. Li, M. You, R. Govindan, R.K. Wilson, E.Y. Kupert, M.W. Anderson, A.G. Schwartz, S.M. Pinney SM, C.I. Amos, J.E. Bailey-Wilson. Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p and 4q. Cancer Epidemiol Biomarkers Prev. 2020;29(2):434‐442. doi:10.1158/1055-9965.EPI-19-0887. PMID: 31826912.