Equipment:
Oxford Nanopore MinION Molecular Sequencer
Details:
The Oxford Nanopore MinION uses nanopores connected to sensor chips to measure disruption of current as a DNA or RNA molecule traverses the pore to determine the sequence. The molecular pore technique can sequence a DNA molecule over a million bases long. Whereas the short reads generated by "Next gen" sequencing are all but useless for tandem repeats. PCR-free sequencing of native DNA or RNA also provides base modification data such as DNA methylation.
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