Primary Research / Clinical / Teaching Interests
Keyword: Clinical Trials, Phase II as Topic

Details:  Experience with calculating sample sizes needed for a given power in phase II trials and estimating the power for different sample sizes in prospective studies. Experience in designing and conducting Bayesian clinical trials where clinician prior information is used for the control therapy, which allows for single-arm trials. Experience in group sequential phase II trials with stopping rules for superiority or inferiority. Experience with designing and conducting Bayesian phase I-II clinical trials where we want to choose a treatment/dose that has high efficacy probability and acceptably low toxicity probability.

MeSH Trace
Health Care
  Environment and Public Health
        Public Health
              Epidemiologic Methods
                    Epidemiologic Study Characteristics as Topic
                          Clinical Trials as Topic
                                Clinical Trials, Phase II as Topic