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Research

 

LSUHSC Research
 

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Research

The LSU Department of Pediatrics maintains an active research environment in both clinical and
basic sciences, and receives research funding from the National Institutes of Health, the Centers
for Disease Control, the Environmental Protection Agency, a number of foundations dedicated to
specific diseases (e.g., American Diabetes Association), and, for the purpose of clinical trials,
various pharmaceutical companies.

Our Research Division is primarily housed at The Research Institute for Children at Children's Hospital
New Orleans. All research is reviewed by the LSU Health Sciences Center Institutional Review Board. Listed below are recent, current or pending projects in the Department of Pediatrics.

 

Allergy/Immunology

Asthma and Obesity: Impact of weight loss on inflammatory markers and clinical manifestations of asthma in children

Asthma and Obesity: Weight Loss and Inflammatory Markers

Creating a low allergen environment in-home and in-schools of asthmatic children: Education and Management

Tuberculosis, a model for Translational Research

Role of IgIV in the induction of antibody response in vitro in patients unresponsive to bacterial vaccine antigens in vivo

Cellular and molecular basis of the immune response in specific antibody deficiency.

Ambulatory Pediatrics and Adolescent Medicine

Resiliency Education to Reduce Depression Disparities_Workgroup, Co-I Pasternak

CPPRN Linked LA County Services Dataset, Co-I Pasternak 

Community Resilience Learning Collaborative and Research Network, Co-I Pasternak 

Community and Patient Partnered Research Network (CPPRN) - Direct Point-of-Service Screening and Enrollment, Co-I: Pasternak

Mind the Gaps: The Contraceptive Experiences of Parenting Adolescents, La-CATS Roadmap Scholar Grant, PI: Dumas

Growing Together: A Mentorship and Support Network for Adolescent Parents, La-CATS Community Scholars, PI: Dumas

Young Mothers Study: A Medical Home Intervention for Parenting Adolescents, LSUHSC Intramural Grant, PI: Dumas

School-Based Medical Clinic Expansion to Provide Adolescent Mental Health Services, PI: Pasternak

Safer Sex Intervention Evaluation,Office of Adolescent Health HRSA, PI: Pasternak (completed)

Clinical Quality Improvement (CQI) for a SBHC Network, PI: Pasternak

Community and Patient Partnered Research Network (CPPRN) PI: Pasternak, Springgate

Growing Young Families Together: Qualitative Exploration of Unmet Needs of Teen Parents, American Academy of Pediatrics PI: Dumas (Completed)

Understanding Kids First Tiger Care Patient Population: Retrospective Data Analysis, PI: Pasternak

NOLA medical home for LGBT Youth: Focus Group Study, PI: Dumas (Completed)

Healthy Families Text: Efficacy of a text-messaging intervention to reduce weight for length percentile and growth velocity in infants 0-18 months at risk for obesity, PI: Lefevre, Co-I Morgan

Critical Care

Residents Perceptions of Social Media and Professionalism

Faculty Development

The Discordance of Ethical Beliefs and Practices in the Management of Chronic Respiratory Failure in Permanently Comatose Children

Incorporating Enhanced Dialogs and Open but Anonymous Audience Attitude Assessments Using a Computerized Audience Response System to Teach Medical Ethics

Examining Perspectives on Physicians’ Duty, Risk and Burden in Quotidian and  Exceptional Conditions

Endocrinology

Mechanisms of Biologic Variation in Hemoglobin Glycation

The Study of Insulin Sensitivity in Low-Birth weight Louisiana Youth (The Silly Study)

Trial Net

Supporting documents [in PDF format] for "Hypokalemia and Alkalosis in Adipsic Hypernatremia are not Associated with Hyperaldosteronism" by by Michael Y. Torchinsky, MD; Stephen Deputy, MD; Fred Rambeau, BS; and Stuart A. Chalew, MD, to be published in Hormone Research

Gastroenterology

Amitriptyline for Moving Children from Tube to Oral Feeding

Neurogastroenterology and Motility

Non-Alcoholic Steatohepatitis

Childhood Obesity

Functional Gastrointestinal Disorders

Magnet Ingestions

Pyloric Flow Measured by Intrapulmonary Impedance

Gabapentin for Feeding Difficulties After Cardiac Surgery

Disability in Children and Adolescents with Irritable Bowel Syndrome (IBS) and/or Fibromyalgia

Hematology/Oncology

Children’s Oncology Group (COG) Clinical Treatment Protocols: We offer the most current protocols for treatment of leukemia, lymphoma, CNS tumors, sarcomas, and other cancers seen in the pediatric population.  We are members of the Pediatric consortium of institutions offering childhood cancer treatment, the Children's Oncology Group (COG), and thus have access to the most recent and promising advances in the understanding and treatment of childhood cancer.

PBMTC clinical treatment protocols

Non-ablative SCT for pediatric hemoglobinopathy patients

Cord blood transplantation in sickle cell disease/thalassemia patients (Celgene-sponsored)

CD34-selected stem cells for transplantation

Co-transfer of Dendritic cell precursors and Cytokine stimullation to accelerate immune recovery following hematopoietic stem cell transplant.

Infectious Disease

Rotavirus VLPs in plants as vaccine candidate

Rotavirus VLPs as vaccine candidates

Development of a vaccine against Helicobacter pylori

Clinical and genetic surveillance of rotavirus in New Orleans

Evaluation of rotavirus vaccine efficacy

Neonatology

Carnitine palmitoyltransferase-1 in neonatal pig heart

Nephrology

Cardiovascular Disease in Chronic Kidney Disease and Dialysis

Cardiovascular Risk in Pediatric Transplant Patients

Multicenter clinical trial of focal glomeruloschelrosis in children and young adults

Mechanisms and Treatment of Inflammation in Chronic Kidney Disease and Dialysis

Malnutrition-Inflammation Complex (MIC) in Chronic Kidney Disease and Dialysis

Prenatal and Perinatal Programming of Adult Hypertension

Tulane Hypertension & Renal Center of Excellence

Research

www.chnola-research.org